NUAK2 Polyclonal Antibody

• Background:

  Catalytic activity:ATP + a protein = ADP + a phosphoprotein., cofactor:Magnesium., enzyme regulation:Activated by phosphorylation on Thr-208 by STK11 in complex with STE20-related adapter-alpha (STRAD alpha) pseudo kinase and CAB39., function:Stress-activated kinase involved in tolerance to glucose starvation. Induces cell-cell detachment by increasing F-actin conversion to G-actin. Expression is induced by CD95 or TNF-alpha, via NF-kappa-B. Protects cells from CD95-mediated apoptosis and is required for the increased motility and invasiveness of CD95-activated tumor cells., PTM:Autophosphorylated in vitro., similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily., similarity:Contains 1 protein kinase domain.

• Gene ID:

  81788

• Swiss Prot:

  Q9H093

• Cross Reactivity:

  Human; Rat; Mouse

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Buffer:

  Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• Molecular Weight:

  69

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  69