LRBA Polyclonal Antibody
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LRBA Polyclonal Antibody
Background :
LPS responsive beige-like anchor protein (LRBA) Homo sapiens The protein encoded by this gene is a member of the WDL-BEACH-WD (WBW) gene family. Its expression is induced in B cells and macrophages by bacterial lipopolysaccharides (LPS) . The encoded protein associates with protein kinase A and may be involved in leading intracellular vesicles to activated receptor complexes, which aids in the secretion and/or membrane deposition of immune effector molecules. Defects in this gene are associated with the disorder common variable immunodeficiency-8 with autoimmunity. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]Gene ID :
987Swiss Prot :
P50851Cross Reactivity :
Human; MouseClonality :
PolyclonalSource :
RabbitApplications :
IHC-p; IF (paraffin section)Dilution :
IHC-p 1:50-300Buffer :
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.Molecular Weight :
314Storage Conditions :
-20°C/1 yearProtein Weight :
314

