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LGMN Polyclonal Antibody

CAT: 1027-RA33075-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA33075-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Legumain (LGMN) Homo sapiens This gene encodes a cysteine protease that has a strict specificity for hydrolysis of asparaginyl bonds. This enzyme may be involved in the processing of bacterial peptides and endogenous proteins for MHC class II presentation in the lysosomal/endosomal systems. Enzyme activation is triggered by acidic pH and appears to be autocatalytic. Protein expression occurs after monocytes differentiate into dendritic cells. A fully mature, active enzyme is produced following lipopolysaccharide expression in mature dendritic cells. Overexpression of this gene may be associated with the majority of solid tumor types. This gene has a pseudogene on chromosome 13. Several alternatively spliced transcript variants have been described, but the biological validity of only two has been determined. These two variants encode the same isoform. [provided by RefSeq, Jul 2008]
Gene ID
5641
Swiss Prot
Q99538
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
47
Storage Conditions
-20°C/1 year
Protein Weight
47

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