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KLOTB Polyclonal Antibody

CAT: 1027-RA32989-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA32989-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Domain:Contains 2 glycosyl hydrolase 1 regions. However, the first region lacks the essential Glu active site residue at position 241, and the second one lacks the essential Glu active site residue at position 889. These domains are therefore predicted to be inactive., function:Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21., similarity:Belongs to the glycosyl hydrolase 1 family., similarity:Belongs to the glycosyl hydrolase 1 family. Klotho subfamily., subunit:Interacts with FGFR1 and FGFR4.
Gene ID
152831
Swiss Prot
Q86Z14
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
114
Storage Conditions
-20°C/1 year
Protein Weight
114

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