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HUWE1 Polyclonal Antibody

CAT: 1027-RA32699-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA32699-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase (HUWE1) Homo sapiens This gene encodes a protein containing a C-terminal HECT (E6AP type E3 ubiquitin protein ligase) domain that functions as an E3 ubiquitin ligase. The encoded protein is required for the ubiquitination and subsequent degradation of the anti-apoptotic protein Mcl1 (myeloid cell leukemia sequence 1 (BCL2-related) ) . This protein also ubiquitinates the p53 tumor suppressor, core histones, and DNA polymerase beta. Mutations in this gene are associated with Turner type X-linked syndromic mental retardation. [provided by RefSeq, Aug 2013]
Gene ID
10075
Swiss Prot
Q7Z6Z7
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; IF (paraffin section)
Dilution
IHC-p 1:50-300
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
481
Storage Conditions
-20°C/1 year
Protein Weight
481