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HBEGF Polyclonal Antibody

CAT: 1027-RA32602-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA32602-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor., PTM:O-linked glycan attachment sites were determined by Edman degradation, O-glycanase digest suggests mucin-type glycosylation (done in HB-EGF purified from histiocytic lymphoma cell line U-937) ., PTM:Several N-termini have been identified by direct sequencing. The forms with N-termini 63, 73 and 74 have been tested and found to be biologically active., similarity:Contains 1 EGF-like domain., subcellular location:Mature HB-EGF is released into the extracellular space and probably binds to a receptor.
Gene ID
1839
Swiss Prot
Q99075
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
22
Storage Conditions
-20°C/1 year
Protein Weight
22

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MBS8571025-01HBEGF Polyclonal Antibody

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