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FBX32 rabbit pAb

CAT: 1027-RA32295-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA32295-01Size:50 µL
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Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]
Product Name Alternative
F-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)
Gene ID
114907
Swiss Prot
Q969P5
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Dilution
WB 1:500-2000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.66% sodium azide.
Molecular Weight
38
Storage Conditions
-20°C/1 year
Protein Weight
38

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