ERCC2 Polyclonal Antibody

• Background:

  ERCC excision repair 2, TFIIH core complex helicase subunit (ERCC2) Homo sapiens The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]

• Gene ID:

  2068

• Swiss Prot:

  P18074

• Cross Reactivity:

  Human; Mouse

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Buffer:

  Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• Molecular Weight:

  83

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  83