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CENPS Polyclonal Antibody

CAT: 1027-RA31562-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA31562-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Centromere protein S (CENPS) Homo sapiens This gene was identified in the neuroblastoma tumor suppressor candidate region on chromosome 1p36. It contains a TFIID-31 domain, similar to that found in TATA box-binding protein-associated factor, TAF (II) 31, which is required for p53-mediated transcription activation. This gene was expressed at very low levels in neuroblastoma tumors, and was shown to reduce cell growth in neuroblastoma cells, suggesting that it may have a role in a cell death pathway. The protein is a component of multiple complexes, including the Fanconi anemia (FA) core complex, the APITD1/CENPS complex, and the CENPA-CAD (nucleosome distal) complex. Known functions include an involvement with chromatin associations of the FA core complex, and a role in the stable assembly of the outer kinetochore. Alternative splicing of this gene results in multiple transcript variants. Naturally occurring read-through transcripts also exist
Gene ID
100526739
Swiss Prot
Q8N2Z9
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
15
Storage Conditions
-20°C/1 year
Protein Weight
15

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