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AT7L3 Polyclonal Antibody

CAT: 1027-RA31203-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA31203-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Domain:The SGF11-type zinc finger mediates the interaction with USP22 and ENY2., function:Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates to a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex., similarity:Belongs to the SGF11 family., similarity:Contains 1 SCA7 domain., similarity:Contains 1 SGF11-type zinc finger., subunit:Component of some SAGA transcription coactivator-HAT complex, at least composed of ATXN7, ATXN7L3, ENY2, GCN5L2, SUPT3H, TAF10, TRRAP and USP22. Within the SAGA complex, ATXN7L3, ENY2 and USP22 form a subcomplex required for histone deubiquitinylation. Interacts directly with ENY2 and USP22.
Gene ID
56970
Swiss Prot
Q14CW9
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.
Molecular Weight
38
Storage Conditions
-20°C/1 year
Protein Weight
38

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