ABCBB Polyclonal Antibody

• Background :

  ATP binding cassette subfamily B member 11 (ABCB11) Homo sapiens The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White) . This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy. [provided by RefSeq, Jul 2008]

• Gene ID :

  8647

• Swiss Prot :

  O95342

• Cross Reactivity :

  Human; Rat; Mouse

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Buffer :

  Liquid in PBS containing 50% glycerol, and 0.02% sodium azide.

• Molecular Weight :

  145

• Storage Conditions :

  -20°C/1 year

• Protein Weight :

  145