IκB-α Polyclonal Antibody
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IκB-α Polyclonal Antibody
Background :
NFKB inhibitor alpha (NFKBIA) Homo sapiens This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]Product Name Alternative :
NFKBIA; IKBA; MAD3; NFKBI; NF-kappa-B inhibitor alpha; I-kappa-B-alpha; IkB-alpha; IkappaBalpha; Major histocompatibility complex enhancer-binding protein MAD3; YM3423Gene ID :
4792Swiss Prot :
P25963Cross Reactivity :
Human; RatClonality :
PolyclonalSource :
RabbitApplications :
WB; IHC-p; IF (paraffin section)Dilution :
WB: 1:2000-5000 IHC: 1:200-500Buffer :
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.Molecular Weight :
40Storage Conditions :
-20°C/1 yearProtein Weight :
40
