GluR4 Polyclonal Antibody

• Background:

  Glutamate ionotropic receptor AMPA type subunit 4 (GRIA4) Homo sapiens Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate) -sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G) . Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq, Jul 2008]

• Product Name Alternative:

  GRIA4; GLUR4; Glutamate receptor 4; GluR-4; GluR4; AMPA-selective glutamate receptor 4; GluR-D; Glutamate receptor ionotropic, AMPA 4; GluA4; YM3382

• Gene ID:

  2893

• Swiss Prot:

  P48058

• Cross Reactivity:

  Human; Rat

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC-p; IF (paraffin section)

• Dilution:

  WB: 1:500-1000 IHC: 1:200-500

• Buffer:

  PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

• Molecular Weight:

  101

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  101