TLE4 Polyclonal Antibody

• Background :

  Caution:Product of a dubious CDS prediction. Found in the 3'UTR of TLE4. No homolog. Large scale identification of a phosphorylated peptide (PubMed:15302935) would require further confirmation., function:Transcriptional corepressor that binds to a number of transcription factors. Inhibits the transcriptional activation mediated by PAX5, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES., similarity:Belongs to the WD repeat Groucho/TLE family., similarity:Contains 7 WD repeats., subunit:Homooligomer and heterooligomer with other family members. Binds PAX5, LEF1, TCF7, TCF7L1 and TCF7L2., tissue specificity:In all tissues examined, mostly in brain, and muscle.

• Product Name Alternative :

  TLE4; KIAA1261; Transducin-like enhancer protein 4

• Gene ID :

  7091

• Swiss Prot :

  Q04727

• Cross Reactivity :

  Human; Mouse; Rat

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC-p; IF (paraffin section) ; ELISA

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight :

  83

• Storage Conditions :

  -20°C/1 year

• Protein Weight :

  83