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THP Polyclonal Antibody

CAT: 1027-RA30455-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA30455-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Uromodulin (UMOD) Homo sapiens The protein encoded by this gene is the most abundant protein in mammalian urine under physiological conditions. Its excretion in urine follows proteolytic cleavage of the ectodomain of its glycosyl phosphatidylinosital-anchored counterpart that is situated on the luminal cell surface of the loop of Henle. This protein may act as a constitutive inhibitor of calcium crystallization in renal fluids. Excretion of this protein in urine may provide defense against urinary tract infections caused by uropathogenic bacteria. Defects in this gene are associated with the renal disorders medullary cystic kidney disease-2 (MCKD2), glomerulocystic kidney disease with hyperuricemia and isosthenuria (GCKDHI), and familial juvenile hyperuricemic nephropathy (FJHN) . Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Product Name Alternative
UMOD; Uromodulin; Tamm-Horsfall urinary glycoprotein; THP
Gene ID
7369
Swiss Prot
P07911
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
70
Storage Conditions
-20°C/1 year
Protein Weight
70

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