Stat5 Polyclonal Antibody

CAT: 1027-RA30126-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:1027-RA30126-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Signal transducer and activator of transcription 5A (STAT5A) Homo sapiens The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X (L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been
Product Name Alternative
STAT5A; STAT5; Signal transducer and activator of transcription 5A; STAT5B; Signal transducer and activator of transcription 5B
Gene ID
6776/6777
Swiss Prot
P42229/P51692
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC-p; IF (paraffin section) ; ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
91
Storage Conditions
-20°C/1 year
Protein Weight
91

Related Products

CatalogName
RA30123-01Stat5 (phospho Ser726/731) Polyclonal Antibody
RA30124-01Stat5 (phospho Tyr694/699) Polyclonal Antibody
RA30125-01Stat5 (phospho-Tyr694) rabbit pAb
RA35076-01STAT2 Polyclonal Antibody
RA35080-01Stat4 Polyclonal Antibody
RA21262-01Stat5a Polyclonal Antibody
RA30103-01Stat2 Polyclonal Antibody
RA30105-01STAT2 Polyclonal Antibody
RA30106-01Stat2 Polyclonal Antibody
RA30116-01Stat3 Polyclonal Antibody

Alternative Products

CatalogName
MBS8592764-01Stat5 Polyclonal Antibody
abx008675-01STAT5 (STAT5) Antibody
APR10272GPolyclonal Stat5 Antibody

Popular Products