SETMAR Polyclonal Antibody

• Background :

  SET domain and mariner transposase fusion gene (SETMAR) Homo sapiens This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

• Product Name Alternative :

  SETMAR; Histone-lysine N-methyltransferase SETMAR; SET domain and mariner transposase fusion gene-containing protein; HsMar1; Metnase

• Gene ID :

  6419

• Swiss Prot :

  Q53H47

• Cross Reactivity :

  Human; Rat; Mouse

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC-p; IF (paraffin section) ; ELISA

• Dilution :

  Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Storage Conditions :

  -20°C/1 year