Rabaptin-5α Polyclonal Antibody

CAT: 1027-RA29171-01Size: 50 µLDry Ice: NoHazardous: No

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CAT#:1027-RA29171-01Size:50 µL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Function:Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Stimulates RABGEF1 mediated nucleotide exchange on RAB5A., PTM:Proteolytic cleavage by caspases in apoptotic cells causes loss of endosome fusion activity., similarity:Belongs to the rabaptin family., subunit:Heterodimer with RABGEF1. The heterodimer binds RAB4A and RAB5A that have been activated by GTP-binding. Binds TSC2, GGA1, GGA2, GGA3, AP1G1 and AP1G2.

Product Name Alternative

RABEP1; RAB5EP; RABPT5; RABPT5A; Rab GTPase-binding effector protein 1; Rabaptin-4; Rabaptin-5; Rabaptin-5alpha; Renal carcinoma antigen NY-REN-17

Gene ID

9135

Swiss Prot

Q15276

Cross Reactivity

Human; Mouse; Rat

Clonality

Polyclonal

Source

Rabbit

Applications

IHC-p; IF (paraffin section) ; ELISA

Dilution

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

Buffer

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Storage Conditions

-20°C/1 year

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