PRAF2 Polyclonal Antibody

• Background :

  Function:May be involved in ER/Golgi transport and vesicular traffic. Plays a proapoptic role in cerulenin-induced neuroblastoma apoptosis., similarity:Belongs to the PRA1 family., subunit:Interacts with CCR5 and GDE1., tissue specificity:Strong expression in the brain, small intestine, lung, spleen, and pancreas as well as in tumor tissues of the breast, colon, lung and ovary, with a weaker expression in normal tissues of the same patient. High expression in neuroblastic tumors. Strongly expressed in Purkinje cells and more moderately in cells of the molecular and the granular layers in the cerebellum. Detected in neuronal cells, but not in non-neuronal cells in the cerebral cortex, hippocampus, and lateral ventricles.

• Product Name Alternative :

  PRAF2; JM4; PRA1 family protein 2

• Gene ID :

  11230

• Swiss Prot :

  O60831

• Cross Reactivity :

  Human; Mouse; Rat

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC-p; IF/ICC; ELISA

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight :

  20

• Storage Conditions :

  -20°C/1 year

• Protein Weight :

  20