PP2B-Aα rabbit pAb

• Background:

  Catalytic activity:A phosphoprotein + H (2) O = a protein + phosphate., cofactor:Binds 1 Fe (3+) ion per subunit., cofactor:Binds 1 zinc ion per subunit., function:Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin. Dephosphorylates HSPB1 and SSH1., online information:Calcineurin entry, similarity:Belongs to the PPP phosphatase family., similarity:Belongs to the PPP phosphatase family. PP-2B subfamily., subcellular location:Colocalizes with ACTN1 and MYOZ2 at the Z line in heart and skeletal muscle., subunit:Composed of two components (A and B), the A component is the catalytic subunit and the B component confers calcium sensitivity. Interacts with TORC2/CRTC2, MYOZ1, MYOZ2 and MYOZ3.

• Product Name Alternative:

  Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform (EC 3.1.3.16; CAM-PRP catalytic subunit; Calmodulin-dependent calcineurin A subunit alpha isoform)

• Gene ID:

  5530

• Swiss Prot:

  Q08209

• Cross Reactivity:

  Human; Mouse; Rat

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Dilution:

  WB 1:1000-2000 ELISA 1:5000-20000

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Storage Conditions:

  -20°C/1 year