POT1 Polyclonal Antibody

• Background :

  Protection of telomeres 1 (POT1) Homo sapiens This gene is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, this protein functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of this gene is associated with stomach carcinogenesis and its progression. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]

• Product Name Alternative :

  POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein

• Gene ID :

  25913

• Swiss Prot :

  Q9NUX5

• Cross Reactivity :

  Human; Monkey

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight :

  70

• Storage Conditions :

  -20°C/1 year

• Protein Weight :

  70