PDGFR α Polyclonal Antibody
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PDGFR α Polyclonal Antibody
Background:
Platelet derived growth factor receptor alpha (PDGFRA) Homo sapiens This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]Product Name Alternative:
Platelet-derived growth factor receptor alpha (PDGF-R-alpha) (PDGFR-alpha) (EC 2.7.10.1) (Alpha platelet-derived growth factor receptor) (Alpha-type platelet-derived growth factor receptor) (CD140 antigen-like family member A) (CD140a antigen) (Platelet-derived growth factor alpha receptor) (Platelet-derived growth factor receptor 2) (PDGFR-2) (CD antigen CD140a)Gene ID:
5156Swiss Prot:
P16234Cross Reactivity:
Human; Mouse; RatClonality:
PolyclonalSource:
RabbitApplications:
WB; ELISADilution:
WB 1:500-2000, ELISA 1:10000-20000Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.Molecular Weight:
193Storage Conditions:
-20°C/1 yearProtein Weight:
193
