PCSK9 rabbit pAb

CAT: 1027-RA28592-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:1027-RA28592-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Cofactor:Calcium., disease:Defects in PCSK9 are the cause of familial hypercholesterolemia 3 (FH3) [MIM:603776]. FH3 inheritance is autosomal dominant., enzyme regulation:Inhibited by EGTA., function:May be implicated in the differentiation of cortical neurons and may play a role in cholesterol homeostasis., PTM:The soluble zymogen undergoes autocatalytic intramolecular processing in the endoplasmic reticulum, resulting in the cleavage of its propeptide that remains associated with the secreted enzyme., similarity:Belongs to the peptidase S8 family., similarity:Contains 1 peptidase S8 domain., subunit:The precursor protein but not the mature protein may form multimers., tissue specificity:Expressed in neuro-epithelioma, colon carcinoma, hepatic and pancreatic cell lines, and in Schwann cells.
Product Name Alternative
Proprotein convertase subtilisin/kexin type 9 (EC 3.4.21.-; Neural apoptosis-regulated convertase 1; NARC-1; Proprotein convertase 9; PC9; Subtilisin/kexin-like protease PC9)
Gene ID
255738
Swiss Prot
Q8NBP7
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
WB 1:1000-2000 ELISA 1:5000-20000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Conditions
-20°C/1 year

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