Ox40 Polyclonal Antibody

• Background :

  TNF receptor superfamily member 4 (TNFRSF4) Homo sapiens The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. [provided by RefSeq, Jul 2008]

• Product Name Alternative :

  TNFRSF4; TXGP1L; Tumor necrosis factor receptor superfamily member 4; ACT35 antigen; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; CD antigen CD134

• Gene ID :

  7293

• Swiss Prot :

  P43489

• Cross Reactivity :

  Human; Mouse; Rat

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IF/ICC; ELISA

• Dilution :

  Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Storage Conditions :

  -20°C/1 year