Nibrin Polyclonal Antibody

• Background :

  Nibrin (NBN) Homo sapiens Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation. [provided by RefSeq, Jul 2008]

• Product Name Alternative :

  NBN; NBS; NBS1; P95; Nibrin; Cell cycle regulatory protein p95; Nijmegen breakage syndrome protein 1

• Gene ID :

  4683

• Swiss Prot :

  O60934

• Cross Reactivity :

  Human; Rat; Mouse

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC-p; IF/ICC; ELISA

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight :

  85

• Storage Conditions :

  -20°C/1 year

• Protein Weight :

  85