MYBPC3 Polyclonal Antibody

• Background :

  Myosin binding protein C, cardiac (MYBPC3) Homo sapiens MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy. [provided by RefSeq, Jul 2008]

• Product Name Alternative :

  Myosin-binding protein C, cardiac-type (Cardiac MyBP-C) (C-protein, cardiac muscle isoform)

• Gene ID :

  4607

• Swiss Prot :

  Q14896

• Cross Reactivity :

  Human; Mouse; Rat

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Dilution :

  WB 1:500-2000, ELISA 1:10000-20000

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight :

  140

• Storage Conditions :

  -20°C/1 year

• Protein Weight :

  140