MLKL Polyclonal Antibody

CAT: 1027-RA27282-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:1027-RA27282-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Mixed lineage kinase domain like (MLKL) Homo sapiens This gene belongs to the protein kinase superfamily. The encoded protein contains a protein kinase-like domain; however, is thought to be inactive because it lacks several residues required for activity. This protein plays a critical role in tumor necrosis factor (TNF) -induced necroptosis, a programmed cell death process, via interaction with receptor-interacting protein 3 (RIP3), which is a key signaling molecule in necroptosis pathway. Inhibitor studies and knockdown of this gene inhibited TNF-induced necrosis. High levels of this protein and RIP3 are associated with inflammatory bowel disease in children. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Sep 2015]
Product Name Alternative
MLKL; Mixed lineage kinase domain-like protein
Gene ID
197259
Swiss Prot
Q8NB16
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
55
Storage Conditions
-20°C/1 year
Protein Weight
55

Related Products

CatalogName
RA21416-01MLKL (phospho S358) Polyclonal Antibody
RA11670-01MLKL mouse Monoclonal Antibody (8H7)
RA10165-01MLKL Mouse Monoclonal Antibody(8H7)
RA10679-01Phospho-MLKL (S358) mouse Monoclonal Antibody (6F8)
RA11844-01Phospho-MLKL (S358) mouse Monoclonal Antibody (6B4)
RA10157-01MLKL(Phospho Ser358) Mouse Monoclonal Antibody(6B4)
RA10156-01MLKL(Phospho Ser358) Mouse Monoclonal Antibody(6F8)
RA36821-01MLKL Phospho-ser358 rabbit pAb
RA36822-01MLKL Phospho-ser345 rabbit pAb
RA27277-01MLK2 Polyclonal Antibody

Alternative Products

CatalogName
MBS8571936-01MLKL Polyclonal Antibody
BS79664MLKL polyclonal antibody

Popular Products