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MCM7 Polyclonal Antibody

CAT: 1027-RA27095-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA27095-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Minichromosome maintenance complex component 7 (MCM7) Homo sapiens The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
Product Name Alternative
DNA replication licensing factor MCM7 (EC 3.6.4.12; CDC47 homolog; P1.1-MCM3)
Gene ID
4176
Swiss Prot
P33993
Cross Reactivity
Human; Rat; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; IF (paraffin section) ; WB
Dilution
IHC-p 1:50-200, WB 1:500-2000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
79
Storage Conditions
-20°C/1 year
Protein Weight
79

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