MCM7 Polyclonal Antibody

• Background :

  Minichromosome maintenance complex component 7 (MCM7) Homo sapiens The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are essential for the initiation of eukaryotic genome replication. The hexameric protein complex formed by the MCM proteins is a key component of the pre-replication complex (pre_RC) and may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. The MCM complex consisting of this protein and MCM2, 4 and 6 proteins possesses DNA helicase activity, and may act as a DNA unwinding enzyme. Cyclin D1-dependent kinase, CDK4, is found to associate with this protein, and may regulate the binding of this protein with the tumorsuppressor protein RB1/RB. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

• Product Name Alternative :

  DNA replication licensing factor MCM7 (EC 3.6.4.12; CDC47 homolog; P1.1-MCM3)

• Gene ID :

  4176

• Swiss Prot :

  P33993

• Cross Reactivity :

  Human; Rat; Mouse

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC-p; IF (paraffin section) ; WB

• Dilution :

  IHC-p 1:50-200, WB 1:500-2000

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight :

  79

• Storage Conditions :

  -20°C/1 year

• Protein Weight :

  79