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MBD3 Polyclonal Antibody

CAT: 1027-RA27066-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA27066-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Methyl-CpG binding domain protein 3 (MBD3) Homo sapiens DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. This gene belongs to a family of nuclear proteins which are characterized by the presence of a methyl-CpG binding domain (MBD) . The encoded protein is a subunit of the NuRD, a multisubunit complex containing nucleosome remodeling and histone deacetylase activities. Unlike the other family members, the encoded protein is not capable of binding to methylated DNA. The protein mediates the association of metastasis-associated protein 2 with the core histone deacetylase complex. Alternative splicing results in multiple transcript variants of this gene. [provided by RefSeq, Jul 2013]
Product Name Alternative
MBD3; Methyl-CpG-binding domain protein 3; Methyl-CpG-binding protein MBD3
Gene ID
53615
Swiss Prot
O95983
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
33
Storage Conditions
-20°C/1 year
Protein Weight
33

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