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JIK Polyclonal Antibody

CAT: 1027-RA26552-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA26552-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Inhibits the basal activity of Jun kinase. Negatively regulated by epidermal growth factor (EGF) . When overexpressed, may activate ERK1/ERK2 and JNK/SAPK., PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily., similarity:Contains 1 protein kinase domain., subcellular location:Also localized to the peripheral cell membrane., subunit:Self-associates., tissue specificity:Ubiquitously expressed at a low level, and highly expressed in peripheral blood leukocytes (PBLs), thymus, spleen, kidney, skeletal muscle, heart and liver.
Product Name Alternative
TAOK3; DPK; JIK; KDS; MAP3K18; Serine/threonine-protein kinase TAO3; Cutaneous T-cell lymphoma-associated antigen HD-CL-09; CTCL-associated antigen HD-CL-09; Dendritic cell-derived protein kinase; JNK/SAPK-inhibitory kinase; Jun kinase-inhi
Gene ID
51347
Swiss Prot
Q9H2K8
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
110
Storage Conditions
-20°C/1 year
Protein Weight
110

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