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INPP5J Polyclonal Antibody

CAT: 1027-RA26372-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA26372-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalytic activity:1D-myo-inositol 1,3,4,5-tetrakisphosphate + H (2) O = 1D-myo-inositol 1,3,4-trisphosphate + phosphate., catalytic activity:D-myo-inositol 1,4,5-trisphosphate + H (2) O = myo-inositol 1,4-bisphosphate + phosphate., domain:The 5 Arg-Ser-Xaa-Ser-Xaa-Xaa (RSXSXX) motifs may constitute binding sites for the 14-3-3 protein., function:Inositol 5-phosphatase, which converts inositol 1,4,5-trisphosphate to inositol 1,4-bisphosphate. Also converts phosphatidylinositol 4,5-bisphosphate to phosphatidylinositol 4-phosphate and inositol 1,3,4,5-tetrakisphosphate to inositol 1,3,4-trisphosphate in vitro. May be involved in modulation of the function of inositol and phosphatidylinositol polyphosphate-binding proteins that are present at membranes ruffles., PTM:Phosphorylated at Ser/Thr residues., similarity:Belongs to the inositol-1,4,5-trisphosphate 5-phosphatase type II family., subcellular location:Predominantly localized to membrane ruffles.
Product Name Alternative
INPP5J; PIB5PA; PIPP; Phosphatidylinositol 4; 5-bisphosphate 5-phosphatase A; Inositol polyphosphate 5-phosphatase J
Gene ID
27124
Swiss Prot
Q15735
Cross Reactivity
Human; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; IF (paraffin section) ; ELISA
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Conditions
-20°C/1 year

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