HDAC8 Polyclonal Antibody

• Background:

  Histone deacetylase 8 (HDAC8) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

• Product Name Alternative:

  HDAC8; HDACL1; CDA07; Histone deacetylase 8; HD8

• Gene ID:

  55869

• Swiss Prot:

  Q9BY41

• Cross Reactivity:

  Human; Mouse; Rat; Monkey

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC-p; IF (paraffin section) ; ELISA

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight:

  42

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  42