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GPS2 Polyclonal Antibody

CAT: 1027-RA25513-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA25513-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
G protein pathway suppressor 2 (GPS2) Homo sapiens This gene encodes a protein involved in G protein-mitogen-activated protein kinase (MAPK) signaling cascades. When overexpressed in mammalian cells, this gene could potently suppress a RAS- and MAPK-mediated signal and interfere with JNK activity, suggesting that the function of this gene may be signal repression. The encoded protein is an integral subunit of the NCOR1-HDAC3 (nuclear receptor corepressor 1-histone deacetylase 3) complex, and it was shown that the complex inhibits JNK activation through this subunit and thus could potentially provide an alternative mechanism for hormone-mediated antagonism of AP1 (activator protein 1) function. [provided by RefSeq, Jul 2008]
Product Name Alternative
GPS2; G protein pathway suppressor 2; GPS-2
Gene ID
2874
Swiss Prot
Q13227
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
40
Storage Conditions
-20°C/1 year
Protein Weight
40

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