FMIP Polyclonal Antibody

• Background:

  Function:May be involved in the differentiation of granulocytes and adipocytes., PTM:Phosphorylated on tyrosine upon binding to activated CSF1R; which causes a dissociation of the two proteins. Phosphorylation on Ser-5 and/or Ser-6 is required for nuclear export. Phosphorylated on Thr-328 in insulin-stimulated adipocytes (By similarity) . Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the THOC5 family., subcellular location:Shuttles between nucleus and cytoplasm., subunit:Interacts with phosphorylated CSF1R., tissue specificity:Ubiquitously expressed.

• Product Name Alternative:

  THOC5; C22orf19; KIAA0983; THO complex subunit 5 homolog; Functional spliceosome-associated protein 79; fSAP79; NF2/meningioma region protein pK1.3; Placental protein 39.2; PP39.2; hTREX90

• Gene ID:

  8563

• Swiss Prot:

  Q13769

• Cross Reactivity:

  Human; Mouse; Rat

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC-p; IF (paraffin section) ; ELISA

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight:

  78

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  78