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FIR Polyclonal Antibody

CAT: 1027-RA24971-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA24971-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Rho-guanine nucleotide exchange factor that activates RAC1. Plays a role in the response to class 3 semaphorins and remodeling of the actin cytoskeleton., similarity:Contains 1 DH (DBL-homology) domain., similarity:Contains 1 FERM domain., similarity:Contains 2 PH domains., subunit:Interacts with PLXNA1. Interaction with PLXNA1 or PIP5K1C lowers its guanine nucleotide exchange activity. Dissociates from PLXNA1 when SEMA3A binds to the receptor. Interacts with PIP5K1C via its FERM domain. The interaction with PIP5K1C is enhanced by SEMA3A binding.
Product Name Alternative
FARP2; KIAA0793; PLEKHC3; FERM; RhoGEF and pleckstrin domain-containing protein 2; FERM domain including RhoGEF; FIR; Pleckstrin homology domain-containing family C member 3; PH domain-containing family C member 3
Gene ID
9855
Swiss Prot
O94887
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF/ICC; ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
119
Storage Conditions
-20°C/1 year
Protein Weight
119

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