Products for Research Use Only
RegisterLogin

FEN-1 Polyclonal Antibody

CAT: 1027-RA24915-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1027-RA24915-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Flap structure-specific endonuclease 1 (FEN1) Homo sapiens The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions
Product Name Alternative
FEN1; RAD2; Flap endonuclease 1; FEN-1; DNase IV; Flap structure-specific endonuclease 1; Maturation factor 1; MF1; hFEN-1
Gene ID
2237
Swiss Prot
P39748
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC-p; IF/ICC; ELISA
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
42
Storage Conditions
-20°C/1 year
Protein Weight
42

Related Products

CatalogName
RA11198-01FEN-1 mouse mAb
RA11199-01FEN-1 mouse mAb
RA29837-01SIRP-α1/β1 Polyclonal Antibody
RA35616-01TSA-1 Polyclonal Antibody
RA35613-01TRβ1 Polyclonal Antibody
RA35608-01Trypsin-1 Polyclonal Antibody
RA30792-01MEK-1 Polyclonal Antibody
RA30740-01Kir4.1 Polyclonal Antibody
RA30367-01TCP-1 ζ Polyclonal Antibody
RA30365-01TCP-1 α Polyclonal Antibody

Alternative Products

CatalogName
MBS2537512-01FEN-1 Polyclonal Antibody
NB100-321Rabbit Polyclonal FEN-1 Antibody
40922-01FEN Polyclonal Antibody
APRab10901-01FEN-1 Rabbit Polyclonal Antibody
C40922FEN-1 Polyclonal Conjugated Antibody
NB100-320APCRabbit Polyclonal FEN-1 Antibody [Allophycocyanin]
NB100-321PERabbit Polyclonal FEN-1 Antibody [PE]
GTR18183082FEN-1 Antibody

Popular Products