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CXCR-3 Polyclonal Antibody

CAT: 1027-RA23907-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA23907-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
C-X-C motif chemokine receptor 3 (CXCR3) Homo sapiens This gene encodes a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-g), CXCL10/IP10 (interferon-g-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell a-chemoattractant) . Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One of the isoforms (CXCR3-B) shows high affinity binding to chemokine, CXCL4/PF4 (PMID:12782716) . [provided by RefSeq, Jun 2011]
Product Name Alternative
CXCR3; GPR9; C-X-C chemokine receptor type 3; CXC-R3; CXCR-3; CKR-L2; G protein-coupled receptor 9; Interferon-inducible protein 10 receptor; IP-10 receptor; CD183
Gene ID
2833
Swiss Prot
P49682
Cross Reactivity
Human; Rat; Mouse; Pig; Chicken
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC-p; IF (paraffin section) ; ELISA
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
37
Storage Conditions
-20°C/1 year
Protein Weight
37

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