COL18A1 Polyclonal Antibody

CAT: 1027-RA23631-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:1027-RA23631-01Size:50 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Collagen type XVIII alpha 1 chain (COL18A1) Homo sapiens This gene encodes the alpha chain of type XVIII collagen. This collagen is one of the multiplexins, extracellular matrix proteins that contain multiple triple-helix domains (collagenous domains) interrupted by non-collagenous domains. A long isoform of the protein has an N-terminal domain that is homologous to the extracellular part of frizzled receptors. Proteolytic processing at several endogenous cleavage sites in the C-terminal domain results in production of endostatin, a potent antiangiogenic protein that is able to inhibit angiogenesis and tumor growth. Mutations in this gene are associated with Knobloch syndrome. The main features of this syndrome involve retinal abnormalities, so type XVIII collagen may play an important role in retinal structure and in neural tube closure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
Product Name Alternative
COL18A1; Collagen alpha-1 (XVIII) chain
Gene ID
80781
Swiss Prot
P39060
Cross Reactivity
Human; Mouse
Clonality
Polyclonal
Source
Rabbit
Applications
IHC-p; IF (paraffin section) ; ELISA
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage Conditions
-20°C/1 year

Related Products

CatalogName
RA23627-01COL14A1 Polyclonal Antibody
RA23632-01COL19A1 Polyclonal Antibody
RA21431-01COL11A1 Polyclonal Antibody
RA23624-01COL13A1 Polyclonal Antibody
RA23625-01COL13A1 Polyclonal Antibody
RA23628-01COL16A1 Polyclonal Antibody
RA23622-01COL12A1 Polyclonal Antibody
RA23623-01COL12A1 Polyclonal Antibody
RA23626-01COL14A1 Polyclonal Antibody
RA23629-01COL17A1 Polyclonal Antibody

Alternative Products

CatalogName
MBS8521996-01COL18A1 Polyclonal Antibody
GT15068-100Col18a1 goat polyclonal antibody
APRab09175-01COL18A1 Rabbit Polyclonal Antibody

Popular Products