C-Kit Polyclonal Antibody

• Background:

  KIT proto-oncogene receptor tyrosine kinase (KIT) Homo sapiens This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor) . Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Product Name Alternative:

  Mast/stem cell growth factor receptor Kit (SCFR; EC 2.7.10.1; Piebald trait protein; PBT; Proto-oncogene c-Kit; Tyrosine-protein kinase Kit; p145 c-kit; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; CD antigen CD117)

• Gene ID:

  3815

• Swiss Prot:

  P10721

• Cross Reactivity:

  Human; Mouse

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC-p; IF (paraffin section) ; WB

• Dilution:

  IHC-p 1:50-200, WB 1:500-2000

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight:

  145

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  145