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AMPKβ2 Polyclonal Antibody

CAT: 1027-RA21861-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:1027-RA21861-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Protein kinase AMP-activated non-catalytic subunit beta 2 (PRKAB2) Homo sapiens The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK) . AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. It is highly expressed in skeletal muscle and thus may have tissue-specific roles. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2013]
Product Name Alternative
PRKAB2; 5'-AMP-activated protein kinase subunit beta-2; AMPK subunit beta-2; YM3447
Gene ID
5565
Swiss Prot
O43741
Cross Reactivity
Human; Mouse; Rat
Clonality
Polyclonal
Source
Rabbit
Applications
WB
Dilution
WB: 1:1000-2000
Buffer
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Molecular Weight
30
Storage Conditions
-20°C/1 year
Protein Weight
30

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