BMP-2 Polyclonal Antibody

• Background:

  Bone morphogenetic protein 2 (BMP2) Homo sapiens This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer, which plays a role in bone and cartilage development. Duplication of a regulatory region downstream of this gene causes a form of brachydactyly characterized by a malformed index finger and second toe in human patients. [provided by RefSeq, Jul 2016]

• Product Name Alternative:

  BMP2; BMP2A; Bone morphogenetic protein 2; BMP-2; Bone morphogenetic protein 2A; BMP-2A

• Gene ID:

  650

• Swiss Prot:

  P12643

• Cross Reactivity:

  Human; Mouse; Rat

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IF/ICC; WB; IHC-p; ELISA

• Dilution:

  IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight:

  44

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  44