GAPDH Polyclonal Antibody
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GAPDH Polyclonal Antibody
Background:
Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) Homo sapiens This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD) . The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferriProduct Name Alternative:
GAPDH; GAPD; CDABP0047; OK/SW-cl.12; Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; Peptidyl-cysteine S-nitrosylase GAPDH; YM3215Gene ID:
2597Swiss Prot:
P04406Cross Reactivity:
Human; Mouse; Rat; Rabbit; Ch; Mk; sheep; XClonality:
PolyclonalSource:
RabbitApplications:
WB; IHC-p; IF (paraffin section)Dilution:
WB: 1:5000 IHC: 1:200Buffer:
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.Molecular Weight:
37Storage Conditions:
-20°C/1 yearProtein Weight:
37
