PEG10 mouse mAb

• Background:

  Paternally expressed 10 (PEG10) Homo sapiens This is a paternally expressed imprinted gene that is thought to have been derived from the Ty3/Gypsy family of retrotransposons. It contains two overlapping open reading frames, RF1 and RF2, and expresses two proteins: a shorter, gag-like protein (with a CCHC-type zinc finger domain) from RF1; and a longer, gag/pol-like fusion protein (with an additional aspartic protease motif) from RF1/RF2 by -1 translational frameshifting (-1 FS) . While -1 FS has been observed in RNA viruses and transposons in both prokaryotes and eukaryotes, this gene represents the first example of -1 FS in a eukaryotic cellular gene. This gene is highly conserved across mammalian species and retains the heptanucleotide (GGGAAAC) and pseudoknot elements required for -1 FS. It is expressed in adult and embryonic tissues (most notably in placenta) and reported to have a role in cell proliferation, differentiation and apoptosis.

• Product Name Alternative:

  AA407948; Edr; Embryonal carcinoma differentiation regulated; Embryonal carcinoma differentiation-regulated protein; HB 1; HB1; KIAA1051; Mammalian retrotransposon-derived protein 2; Mar2; Mart2; MEF3 like 1; MEF3-like protein 1; MEF3L; MEF3L1; MyEF 3; Myelin expression factor 3-like protein 1; Paternally expressed 10; Paternally expressed gene 10 ORF1; Paternally expressed gene 10 protein; Peg10; PEG10 protein; PEG10_HUMAN; Putative uncharacterized protein PEG10; Retrotransposon gag domain containing 3; Retrotransposon gag domain-containing protein 3; Retrotransposon-derived gag-like polyprotein; Retrotransposon-derived protein PEG10; RGAG3; Ty3/Gypsy-like protein.

• Gene ID:

  23089

• Swiss Prot:

  Q86TG7

• Cross Reactivity:

  Human

• Clonality:

  Monoclonal

• Source:

  Mouse

• Applications:

  WB; IP

• Dilution:

  Wb 1:1000

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight:

  55

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  55