Products for Research Use Only

NF κB P50 Mouse mAb (5D2)

CAT: 1027-RA11742-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1027-RA11742-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Nuclear factor kappa B subunit 1 (NFKB1) Homo sapiens This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Alternative splicing results in multiple transcript variants encoding different isof
Product Name Alternative
Nuclear factor NF-kappa-B p105 subunit (DNA-binding factor KBF1) (EBP-1) (Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1) [Cleaved into: Nuclear factor NF-kappa-B p50 subunit]
Gene ID
4790
Swiss Prot
P19838
Cross Reactivity
Human
Clonality
Monoclonal
Source
Mouse
Applications
IHC-p; WB
Dilution
IHC-p1:50-200 , WB 1:1000-2000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.61% sodium azide.
Molecular Weight
50
Storage Conditions
-20°C/1 year
Protein Weight
50