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Lamin A mouse mAb

CAT: 1027-RA11595-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:1027-RA11595-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Lamin A/C (LMNA) Homo sapiens The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome. [provided by RefSeq, Apr 2012]
Product Name Alternative
70 kDa lamin ; CDCD1 ; CDDC ; CMD1A ; CMT2B1 ; EMD2 ; FPL ; FPLD ; HGPS ; IDC ; LAMIN A ; lamin A/C ; LAMIN C ; Lamin-A/C ; LDP1 ; LFP ; LGMD1B ; LMN 1 ; LMN A ; LMN C ; LMN1 ; LMNA ; LMNA_HUMAN ; LMNC ; NY REN 32 antigen ; PRO1 ; Renal carcinoma antigen NY-REN-32
Gene ID
4000
Swiss Prot
P02545
Cross Reactivity
Human; Mouse; Rat
Clonality
Monoclonal
Source
Mouse
Applications
WB
Dilution
Wb dilution 1:1000
Buffer
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Molecular Weight
74
Storage Conditions
-20°C/1 year
Protein Weight
74

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