HP1-γ mouse mAb

• Background:

  Chromobox 3 (CBX3) Homo sapiens At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]

• Product Name Alternative:

  CBX 3; CBX3 ; CBX3_HUMAN; Chromobox homolog 3 (HP1 gamma homolog, Drosophila) ; Chromobox homolog 3; Chromobox protein homolog 3 ; GAMMA; HECH; Heterochromatin like protein 1; Heterochromatin protein 1 homolog gamma; Heterochromatin protein HP1 gamma; HP1 gamma; HP1 gamma homolog; HP1Hs gamma; Modifier 2 protein.

• Gene ID:

  11335

• Swiss Prot:

  Q13185

• Cross Reactivity:

  Mouse; Human; Monkey; Hamster; Rat

• Clonality:

  Monoclonal

• Source:

  Mouse

• Applications:

  WB; IF/ICC; IP; IHC

• Dilution:

  Wb 1:1000 icc 1:200

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight:

  22

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  22