HDAC3 mouse mAb

• Background:

  Histone deacetylase 3 (HDAC3) Homo sapiens Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]

• Product Name Alternative:

  HD 3; HD3; HDAC 3; HDAC3; HDAC3_HUMAN; Histone deacetylase 3 (HD3) (RPD3-2) ; histone deacetylase 3; RPD 3; RPD3 2; RPD3; RPD3-2; SMAP 45; SMAP45.

• Gene ID:

  8841

• Swiss Prot:

  O15379

• Cross Reactivity:

  Human; Mouse; Rat

• Clonality:

  Monoclonal

• Source:

  Mouse

• Applications:

  WB

• Dilution:

  Wb 1:1000

• Buffer:

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight:

  49

• Storage Conditions:

  -20°C/1 year

• Protein Weight:

  49