Bax mouse mAb

• Background :

  The protein encoded by BAX (BCL2 associated X, apoptosis regulator) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regulated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. Multiple alternatively spliced transcript variants, which encode different isoforms, have been reported for BAX.

• Product Name Alternative :

  Apoptosis regulator BAX; Apoptosis regulator BAX cytoplasmic isoform beta; Apoptosis regulator BAX membrane isoform alpha; BAX; Bax isoform psi; BAX protein cytoplasmic isoform delta; Bax protein cytoplasmic isoform delta.; Bax protein cytoplasmic isoform gamma; Bax zeta; Bax-protein; BAX_HUMAN; BAXA; Bcl-2-like protein 4; BCL2 associated X protein; BCL2 associated X protein omega; BCL2 associated X protein transcript variant delta2; Bcl2-L-4; BCL2L4; membrane isoform alpha.

• Gene ID :

  581

• Swiss Prot :

  Q07812

• Cross Reactivity :

  Human; Monkey

• Clonality :

  Monoclonal

• Source :

  Mouse

• Applications :

  WB

• Dilution :

  Wb dilution 1:1000

• Buffer :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Molecular Weight :

  20

• Storage Conditions :

  -20°C/1 year

• Protein Weight :

  20