Ganirelix

• Description:

  Ganirelix acetate is a synthetic decapeptide with high antagonistic activity against naturally occurring gonadotropin-releasing hormone (GnRH) . Ganirelix acetate is derived from native GnRH with substitutions of amino acids at positions 1, 2, 3, 6, 8, and 10 to form the following molecular formula of the peptide: N-acetyl-3- (2-napthyl) -D-alanyl-4-chloro-D-phenylalanyl-3- (3-pyridyl) -D-alanyl-L-seryl-L-tyrosyl-N 9 , N 10 -diethyl- D-homoarginyl-L-leucyl-N 9 , N 10 -diethyl-L-homoarginyl-L-prolyl-D-alanylamide acetate. The molecular weight for Ganirelix acetate is 1570.4 Dalton as an anhydrous free base.

• Buffer:

  The Ganirelix hormone (0.5 mg/mL) contains 0.1 mg acetic acid and 23.5 mg mannitol pH-5.

• Storage Conditions:

  Ganirelix should be stored between 2°C- (-30°C) at all time.