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Cyclin B2 [SD2045] Antibody

CAT: 1071-OM637541-01Size: 100 µLDry Ice: NoHazardous: No
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CAT#:1071-OM637541-01Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
In eukaryotic cells, mitosis is initiated following the activation of a protein kinase known variously as maturation-promoting factor, M-phase specific histone kinase or M-phase kinase. This protein kinase is composed of a catalytic subunit (Cdc2), a regulatory subunit (cyclin B) and a low molecular weight subunit (p13-Suc 1) . The Cdc/cyclin enzyme is subject to multiple levels of control of which the regulation of the catalytic subunit by tyrosine phosphorylation is the best understood. Tyrosine phosphorylation inhibits the Cdc2/cyclin B enzyme and tyrosine dephosphorylation, occurring at the onset of mitosis, directly activates the pre-MPF complex . Evidence has established that B-type cyclins not only act on M-phase regulatory subunits of the Cdc2 protein kinase, but also activate the Cdc25A and Cdc25B endogenous tyrosine phosphatase, of which Cdc2 is the physiological substrate. The two B-type cyclins, cyclin B1 and cyclin B2, have been shown to have distinct tissue distributions.
Immunogen
Recombinant protein
Antibody Type
Primary Antibodies
Product Name Synonym
Ccnb2 antibody CCNB2_HUMAN antibody CycB2 antibody Cyclin B2 antibody G2 mitotic specific cyclin B2 antibody G2/mitotic specific cyclin B2 antibody G2/mitotic-specific cyclin-B2 antibody HsT17299 antibody MGC108931 antibody MGC140694 antibody

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